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Is Vitamin D An Antioxidant

Which Vitamins Are Antioxidants

Vitamin E, a potent antioxidant

The term antioxidants is often used as a buzzword in marketing. But its important to understand what they are and which vitamins and minerals serve as antioxidants so that you can incorporate them into your daily life. There are a variety of substances that can act as antioxidantssome more well-known than others. Follow along with Centrum to learn more.

Study Confirms Significant Effect Of Vitamin D Level On Levels Of Glutathione Gssg And Cysteine

A study by Alvarez et al. looked at the bloodwork from 693 healthy adults which measured their vitamin D levels, plasma glutathione, cysteine , and multiple inflammatory markers to see what relationships existed. They found that vitamin D levels were positively associated with plasma glutathione and negatively associated with both GSSG and cysteine . These associations remained statistically significant even after adjusting for other factors.

Bottom Line On Antioxidants And Disease Prevention

Excessive free radicals contribute to chronic diseases including cancer, heart disease, cognitive decline, and vision loss. This doesnt automatically mean that substances with antioxidant properties will fix the problem, especially if they are taken out of their natural context. The studies so far are inconclusive but generally dont provide strong evidence that antioxidant supplements have a substantial impact on disease. Keep in mind that most of the trials conducted have had fundamental limitations due to their relatively short duration and inclusion of people with existing disease. At the same time, abundant evidence suggests that eating whole in fruits, vegetables, and whole grainsall rich in networks of naturally occurring antioxidants and their helper moleculesprovides protection against many scourges of aging.

  • National Center for Complementary and Integrative Health . Antioxidants: In Depth. Accessed 7/1/19.
  • Carlsen MH, Halvorsen BL, Holte K, Bøhn SK, Dragland S, Sampson L, Willey C, Senoo H, Umezono Y, Sanada C, Barikmo I. The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide. Nutrition journal. 2010 Dec 9:3.
  • Semba RD, Ferrucci L, Bartali B, Urpí-Sarda M, Zamora-Ros R, Sun K, Cherubini A, Bandinelli S, Andres-Lacueva C. Resveratrol levels and all-cause mortality in older community-dwelling adults. JAMA internal medicine. 2014 Jul 1 174:1077-84.
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    Are Excess Amounts Of Water Soluble Vitamins Eliminated In Urine

    Water-soluble vitamins are those that are dissolved in water and readily absorbed into tissues for immediate use. Because they are not stored in the body, they need to be replenished regularly in our diet. Any excess of water-soluble vitamins is quickly excreted in urine and will rarely accumulate to toxic levels.

    Blood Sampling And Biochemical Assays

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    Before any intervention, a 10ccs blood sample was obtained from the antecubital vein of the left hand. The blood sampling was repeated 72h after the last session of the training. The blood samples were centrifuged at 22002500rpm for 10min and plasma and the surface layer were separated from haematocrits. The plasma samples were used for the measurement of TAC, MDA, SOD, and GPX and Creatine Kinase , and 25D.

    The SOD and GPX activity was measured by using a commercially available kit , and were expressed in U/L. Similarly, a commercially available kit was used for the measurement of the antioxidant capacity in the plasma . The plasma MDA was measured based on the method of Buege and Aust . The plasma CK activity was tested using a standard kit and enzyme activity was expressed as U/L.

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    Looking For A Vitamin D Supplement

    We did the research for you. See Healthlines picks for the 13 best vitamin D supplements.

    Several factors can affect your ability to get adequate vitamin D from sunlight alone.

    You may be less likely to absorb enough vitamin D from the sun if you (

    • severe bone or muscle pain or weakness
    • stress fractures, especially in your legs, pelvis, and hips

    A healthcare professional can diagnose a vitamin D deficiency by performing a simple blood test. If you have a deficiency, your doctor may order X-rays to check the strength of your bones.

    If you receive a diagnosis of vitamin D deficiency, a healthcare professional will likely recommend that you take vitamin D supplements. If you have a severe deficiency, they may instead recommend high dose vitamin D tablets or liquids.

    You should also make sure to get vitamin D through sunlight and the foods you eat.

    Benefits Of Vitamin D For Skin

    Dhingra says the chief function of vitamin D is maintaining a calcium balance in our bodies, but it also has functions well beyond thisfor instance, the role it plays in skin health. As Zeichner puts it, “Generally speaking, skin health is best improved when your body has a full store of vitamin D.” Below are the main ways vitamin D benefits the skin.

    • “The most important practical use of Vitamin D in the skin to date is as a mild-to-moderate anti-inflammatory, used clinically as a cream in the treatment of conditions like psoriasis, eczema, and vitiligo,” Dhingra says. “Vitamin D dials down exuberant inflammation, alleviating symptoms for those suffering from these conditions.”
    • Protects the skin: Dhingra adds that vitamin D functions as a steroid, working within a cells nucleus to stimulate proliferation, regulate function, and potentially stabilize genes. A 2012 review suggests that Vitamin D may play a protective role in cancers broadly, and skin cancer specifically.
    • Herrmann and Gerstner say as an antioxidant, topical vitamin D can also squelch damaging environmental oxidants that cause premature aging.
    • Normalizes cell turnover: As Zeichner points out, vitamin D analogs have been shown to normalize cell turnover and prevent the build-up of dead cells on the skin’s surface that lead to psoriasis plaques.

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    Assessment Of Dietary Intakes

    Usual fruits and vegetables intakes of the participants were assessed using a validated 50-item semi-quantitative food frequency questionnaire . Validity and reproducibility of the semi-FFQ had previously been assessed before. The frequency of fruits and vegetables consumption was asked as daily, weekly, and monthly for each item. In case of aphasia, the patient’s spouse answered the questions.

    Antioxidant Effect Of Vitamin D Supplementation In Subjects With Diabetes

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    Yiu et al. investigated the effects of 5000 IU vitamin D daily supplementation for a 12-week period, in a group of subjects with T2D, on vascular function and some oxidative stress biomarkers, such as serum isoprostanes and SOD levels. Results from this trial showed that despite the improvement in 25D status, vitamin D supplementation did not achieve an improvement in the oxidative end-points considered by the authors. All subjects enrolled in the trial had suboptimal 25D status at baseline, showing a significant increase in serum 25D concentration post-supplementation at follow-up compared with the placebo group ng/ml). The authors did not assess dietary intake. In a recent double-blind placebo-controlled trial, Tamadon et al. administered 50 000 IU cholecalciferol to diabetic haemodialysis patients every week for 12 weeks. The vitamin D-treated group showed increased TAC v. 2·0 mmol/l P=0·04) and reduced MDA levels v. +0·1 mol/l P=0·009) compared with the placebo group. However, these results, while showing statistical significance, fail to show clinical significance.

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    Research Spotlight: Resistance Training Boosts Your Antioxidant System More Than Vitamin D Supplementation

    Vitamin D serves a plethora of functions in the human body, but one of its major functions is to regulate the endogenous antioxidant system. When most people think of antioxidants, they immediately think of vitamins that directly scavenge free radicals , or possibly phytochemicals with antioxidant properties. However, much of your bodys antioxidant capacity comes from its own endogenous antioxidant system proteins and compounds your body produces, which scavenge free radicals.

    Vitamin D is far from the only thing that influences your endogenous antioxidant system. Importantly, exercise plays an important role as well. As part of the adaptive response to exercise-induced inflammation, your body ramps up endogenous antioxidant production, so that subsequent exercise bouts will cause less oxidative stress.

    Before and after the eight-week intervention, blood draws were performed to assess malondialdehyde , superoxide dismutase , total antioxidant capacity , glutathione peroxidase , creatine kinase , and serum vitamin D levels.

    Which Vitamin Acts As An Antioxidant

  • Parting Words
  • So, you must have heard that antioxidants can be had from vitamin-rich foods and supplements. But are all 13 vitamins considered as that? If not, then which vitamin acts as an antioxidant?

    The truth is not all vitamins have antioxidant properties. In this article, we will show you three known antioxidant vitamins and one that is potentially a free-radical weapon.

    But before that, let us learn more about antioxidants and free radicals.

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    Are Vitamin K And Vitamin D Antioxidant

    Are vitamin k and vitamin d antioxidant? Some of the ignored antioxidant vitamins are Vitamin K, Vitamin D, Niacin, Pyridoxine, and Riboflavin, which act as co-enzyme in many cases to attack free radicals and, their deficiency states precipitate oxidative stress.

    Is vitamin D an antioxidant vitamin? Vitamin D is a membrane antioxidant: thus Vitamin D3 and its active metabolite 1,25-dihydroxycholecalciferol and also Vitamin D2 and 7-dehydrocholesterol all inhibited iron-dependent liposomal lipid peroxidation.

    Does vitamin K act as an antioxidant? The results show that the vitamin K cycle could act as a potent antioxidant, that the active species in all probability is vitamin K-hydroquinone, and that the primary reaction product is the semiquinone.

    Which vitamin is an antioxidant? Examples of antioxidants include vitamins C and E, selenium, and carotenoids, such as beta-carotene, lycopene, lutein, and zeaxanthin.

    Determination Of Retinyl Acetate Retinyl Palmitate

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    Vitamin A content was expressed as g RE per serving using the following factors: 0.872, 0.546, and 0.167, respectively, for retinyl acetate, retinyl palmitate, and -carotene. Vitamin E content was expressed as mg -TE per serving using the factor 0.91 for -tocopheryl acetate . A serving portion refers to the daily intake recommended by the supplement manufacturer.

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    Vitamin D And Mitochondrial Health

    Vitamin D deficiency and insufficiency, when combined typically defined as 25D concentrations < 50 nmol/L, are associated with muscle atrophy and deficits in muscle strength in several clinical models . While many studies of vitamin D deficiency and insufficiency focus on its impact on protein synthesis and degradation, there is also a growing body of evidence to suggest that vitamin D supplementation in deficient individuals improves measures of mitochondrial density and function . These studies are supported by research in rodent models, where vitamin D supplementation in deficient animals improves the balance between muscle protein synthesis and degradation, as well as measures of mitochondrial density and function .

    What Are The Best Antioxidant Foods

    Vegetables and fruit tend to be packed full of antioxidants. Eating a wide variety of them can help ensure you get a diverse range of different antioxidants to optimise your health. There are hundreds of antioxidants in not only fruit and vegetables, but nuts, seeds, olive oil and wholegrains.

    You can get the following antioxidants from these food sources:

    • Vitamin A liver, sweet potatoes, carrots, milk and egg yolks
    • Vitamin C broccoli, Brussels sprouts, cauliflower
    • Vitamin E almonds, avocado, leafy greens
    • Carotenoids apricots, asparagus, broccoli
    • Zinc beef, oysters, pumpkin seeds
    • Selenium Brazil nuts, fish, shellfish
    • Beta-carotene carrots, pumpkin, sweet potato, spinach
    • Lycopene tomato, watermelon, grapefruit.

    The Australian Dietary Guidelines outline the types of foods you should be eating to reduce your risk of diet-related conditions and chronic diseases.

    In some cases, your doctor may recommend you take antioxidant supplements if your diet is inadequate.

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    Best Veggie Supplement: Sunwarrior Clean Green & Protein


    • A great source of protein, calcium, and iron.
    • Includes organic fermented pea protein.
    • Soy-free, gluten-free, dairy-free, non-GMO, vegan.

    This Sunwarrior blend includes natural plant-based proteins to help you build lean muscle, and a blend of vegetables with broccoli, onion extract, tomatoes, carrots, spinach, kale, and brussels sprouts. Ingredients like goji berries, yellow peas, and coconut add even more natural antioxidants.

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    What Are Antioxidants

    What Are Antioxidant Vitamins? | Vitamins

    Antioxidants are molecules that fight free radicals in your body.

    Free radicals are compounds that can cause harm if their levels become too high in your body. Theyre linked to multiple illnesses, including diabetes, heart disease, and cancer.

    Your body has its own antioxidant defenses to keep free radicals in check.

    However, antioxidants are also found in food, especially in fruits, vegetables, and other plant-based, whole foods. Several vitamins, such as vitamins E and C, are effective antioxidants.

    Antioxidant preservatives also play a crucial role in food production by increasing shelf life.


    Free radicals are constantly being formed in your body.

    Without antioxidants, free radicals would cause serious harm very quickly, eventually resulting in death.

    However, free radicals also serve important functions that are essential for health (

    As a result, your body needs to maintain a certain balance of free radicals and antioxidants.

    When free radicals outnumber antioxidants, it can lead to a state called oxidative stress.

    Prolonged oxidative stress can damage your DNA and other important molecules in your body. Sometimes it even leads to cell death.

    Damage to your DNA increases your risk of cancer, and some scientists have theorized that it plays a pivotal role in the aging process .

    Several lifestyle, stress, and environmental factors are known to promote excessive free radical formation and oxidative stress, including:

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    How To Take/apply It

    When taking a vitamin D supplement, Zeichner recommends doing so along with a fatty meal of healthy fats, for best absorption.

    If using a topical vitamin D prescription, follow the application instructions from your doctor. If you choose to use a topical vitamin D for anti-aging, Herrmann says combining it with other antioxidant vitamins, growth factors, or retinoids can create a “super” product, working on multiple anti-aging pathways.

    Vitamin D can also be found in some over-the-counter beauty products. “Medically, I often use a prescription cream-based vitamin D analogue to maintain clearness for psoriasis and other inflammatory skin diseases,” Dhingra says. However, Dhingra adds that outside of its clinical uses in fighting inflammatory skin diseases, the evidence is not concrete enough to strongly recommend everyone implement a vitamin D-based product in their skincare line for normal skin health.

    For sun-stimulated vitamin D, Dhingra says sunscreen is critical, as well as limiting exposure to no more than 10 to 15 minutes daily, and minimizing the amount of skin you expose.

    Smoking Increases Vitamin C Needs

    Smoking causes many types of cancers, largely because cigarette smoke contains toxins that cause oxidative damage to your bodys cells .

    Because of this increased exposure to free radicals, research suggests that people who smoke need 35 mg more of vitamin C per day than people who dont smoke. Similarly, exposure to secondhand smoke also increases vitamin C needs .

    Yet, this additional need for vitamin C can be easily met through diet and without taking antioxidant supplements.


    For the most part, the use of antioxidant supplements is discouraged, though the antioxidant vitamin C can benefit people with the common cold or those who smoke. Still, needs can often be met through diet instead of supplements.

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    Side Effects Of Vitamin D

    Zeichner says topical vitamin D is generally safe to use daily, but like any skincare product, Dhingra says it could cause irritation, depending on how its created. Herrmann warns that many of these products are oil-based, which could be too heavy in acne-prone skin and cause pore-clogging.

    When taken orally, Dhingra says its fairly difficult to consume a significantly excessive amount of vitamin D, but he says that the fat-soluble vitamin can cause excess calcium buildup with nausea, vomiting, mental changes, increased urination, and kidney failure. “This is only ever in the setting of extreme supplementation, which should only be done with a qualified medical professional,” Dhingra says. In general, Gerstner recommends not exceeding 4000 IU a day, but always check with your physician and discuss any supplements or vitamins before adding them to your regimen.

    What Is An Antioxidant

    9.12 What is an Antioxidant?

    An antioxidant is a general term for any compound that can counteract unstable molecules, called free radicals. According to Harvard Health, free radicals can cause damage to DNA, cell membranes and other parts of cells.i

    Although free radicals are damaging by nature, they are unavoidable. The body generates free radicals in response to environmental factors like ultraviolet rays or air pollution.i

    Since these molecules are so pervasive, we need antioxidants to come in and disarm them. Antioxidants neutralize free radicals by giving up some of their own electrons. In doing this, they act as a natural off switch for free radicals, which helps break a chain reaction that can affect other cells in the body.i

    The cells in your body naturally produce some antioxidants, but certain vitamins and minerals found in the foods that you eat or supplements that you take are also sources of antioxidants.i

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    Vitamin D Role In Antioxidant

    This downregulation of the gene through the purple tomato intake can also make contributions to decrease prostate most cancers chance via limiting cell proliferation. The pink tomato seemed to paintings higher than the yellow

    And, lycopene by myself appreciably upregulated procarcinogenic genes.

    Get Your Antioxidants From Food

    Getting antioxidants from food rather than supplements is much safer and healthier.

    All foods contain different antioxidants in varying amounts, so its important to include a variety of foods in your diet.

    While animal-based products, such as eggs and dairy products, have antioxidants, plant-based foods are particularly high in them (

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