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What Is Vitamin B12 5000 Mcg Sublingual

Introducing The Liquid Vitamin B12 Sublingual

Pros & Cons of Sublingual Liquid B12

Vitamin B12 is arguably one of the most important nutrients that most people are unawaringly deficient in, because unlike other nutrients, the body cannot synthesize it on its own and neither does it store it for long. Therefore, there is a need for consistent and regular supplementation if you are to maintain healthy levels throughout the year.

The nutriment plays a quite significant role in a number of physiological and biological functions in our bodies such as DNA synthesis, the manufacture of red blood cells, maintenance of optimal brain health among others.

TIdeally, our bodies B12 needs can be met by the regular consumption of fresh , organic and unrefined food. However, it is becoming exceedingly hard to rely on just our standard-everyday diet to furnish our bodies with a nutriment whose deficiency can lead to serious health complications, especially for those who follow a strict plant-based eating regimen. Eggs, poultry, meat, liver, fish and other animal dairy products, which dont feature on their menu, are regarded as the standard sources of dietary B12.

In fact, without external supplementation, strict vegetarians are at risk of suffering from a serious lack of this nutriment as B12 from most plant sources is not as easily absorbed or readily bioavailable as that from animal products.

Vitamin B12 5000 Mcg Nuggets

Vitamin B12 is part of a group of essential nutrients known as the B Complex. It supports energy metabolism and promotes a healthy nervous system. Along with folic acid and vitamin B6 it supports heart health by promoting healthy levels of homocysteine already within a normal range. B12 is required for the normal development and regeneration of red blood cells, which help to deliver oxygen throughout the body. In addition, B12 is involved in DNA synthesis and renewal. This formulation provides high potency vitamin B12 in a convenient nugget form that is also suitable for vegans.*

  • Available In
*Daily Value not established

Customer Questions And Answers

Please ask any questions you may have about this specific product in the field below.

Your question and our corresponding answer will not be confidential and will be posted publically on this specific product page.

Additionally, PureFormulas is unable to directly recommend products in relation to specific health conditions. Please contact your trusted healthcare practitioner for direct product recommendations.

If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Your healthcare professional is the best source for guidance before beginning an exercise or nutritional supplement program.

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What Happens When You Take B12 Vitamins

Vitamin B12 is a nutrient that helps keep the bodys nerve and blood cells healthy and helps make DNA, the genetic material in all cells. Vitamin B12 also helps prevent a type of anemia called megaloblastic anemia that makes people tired and weak. Two steps are required for the body to absorb vitamin B12 from food.

Where To Find Vitamin B1:

Solgar Sublingual Methylcobalamin (Vitamin B12) 5000 mcg ...

Physician Naturals SimplyPure Methyl Cobalamin B12 Quick Dissolve Sublingual with maximum available dosage of 5000 Mcg Ultra Absorption Supplement is active immediately upon absorption, while cyanocobalamin must be converted to methylcobalamin by the body before it can be used. Methylcobalamin B12 is the neurologically active form of B 12 is the largest and most complex vitamin currently known to stimulate. A slight deficiency of vitamin B-12 can lead to anemia, fatigue, mania, and depression, It is essential for maintaining the integrity of the nervous system. A deficiency principally affects the peripheral nerves and, in later stages, the spinal cord. Check the Supplement Facts label to determine the amount of vitamin B12 provided.

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B12 For Memory And Mood

Its commonly thought that taking vitamin B12 can boost your memory and mood. However, theres not a lot of evidence to support this theory.

Animal studies suggest that vitamin B12 deficiency has been associated with memory impairment. Yet, theres currently no evidence that B12 supplements improve memory in humans who arent deficient .

In a large review, vitamin B12 supplements had no effect on depressive symptoms in the short term but may help prevent relapse over the long term (

There are no specific dosage recommendations for B12 supplements for mental performance or mood.


Optimal dosing of vitamin B12 varies by age, lifestyle, and dietary needs. The general recommendation for adults is 2.4 mcg. Older adults, as well as pregnant and breastfeeding women, require higher doses.

Solgar Sublingual Methylcobalamin 5000 Mcg 60 Nuggets

  • June 1 2024 Expiration Date

    The length of time for the expiration date or “best used before” date depends on the type of product, as well as the brand.

    Perishable items generally have shorter expiration dates. Although our warehouse is fully air-conditioned, these more fragile items are put in cold storage for maximum freshness.

    Our receiving department does its best to verify and then enter the correct expiration dates for all incoming products. However, discrepancies do occur from time to time. This being said, the exceptionally high turnover at iHerb ensures that our inventory is among the freshest in the industry.

  • Date First Available: November 13 2008
  • Shipping Weight:Switch to Imperial unitsShipping WeightThe Shipping Weight includes the product, protective packaging material and the actual shipping box. In addition, the Shipping Weight may be adjusted for the Dimensional Weight of a package. It is important to note that certain types of products will often require protective packaging material. As such, these products will reflect a higher Shipping Weight compared to the unprotected product.
  • Product code: SOL-01959
  • 5.1 x 5.1 x 8.9 cm , 0.11 kgSwitch to Imperial units
  • Active Coenzyme Form of B12
  • Gluten, Wheat & Dairy Free
  • K-Parve
  • Dietary Supplement

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Vitamin B12 Megadose Is More Always Better

Extreme vitamin B12 extra high dose! This is how some manufacturers advertise their vitamin B12 products. Yet are such high doses of the vitamin genuinely useful?

Vitamin B12 is a healthy and vital vitamin, which benefits the body in many ways. This sometimes leads people to believe that the more they consume, the healthier they will become a sentiment that is only true to a very limited extent. If optimal doses are exceeded, vitamins can upset the bodys sensitive balance and overburden the excretory organs.

To this end, megadoses of vitamin B12 should be criticised: they are unnecessarily high for meeting the bodys requirement. But are there any instances where this kind of B12 dosage can be helpful?

B12 For Improved Energy

Natural Factors B 12 Methylcobalamin Sublingual 5000mcg with Dr. Michael T. Murray

Though vitamin B12 is commonly taken to increase energy levels, evidence showing that B12 supplements improve energy levels in people without a deficiency is lacking.

However, B12 supplements have been found to improve energy levels in those who are deficient in this nutrient .

One review recommended that those with vitamin B12 deficiency take 1 mg of vitamin B12 daily for a month, followed by a maintenance dose of 125250 mcg per day .

People who have issues absorbing vitamin B12, such as those with Crohns disease or other gastrointestinal issues, may benefit from B12 injections, which bypass the need for absorption by the digestive tract .

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The Gold Standardsince 1947

For over 70 years Solgar® has been committed to quality, health, and well-being. Our ongoing mission is to create the finest nutritional supplements in small batches, made possible through tireless research, using only the finest raw materials.

When it comes to quality, Solgar® is The Gold Standard.

Lozenges Drops And Sprays

There are a number of vitamin B12 supplements which utilise sublingual absorption:

  • Vitamin B12 lozenges
  • Vitamin B12 drops and sprays
  • Vitamin B12 strips
  • Vitamin B12 toothpaste

Drops and sprays are administered directly under the tongue, whereas strips and lozenges dissolve slowly under the tongue. These forms of supplements are particularly convenient for children and adults who have problems swallowing tablets and capsules.

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The Two Forms Of Vitamin B12 You Need To Know

Vitamin B12 is the largest and most complex vitamin we know today. In supplements, it comes in two primary forms: methylcobalamin or cyanocobalamin.

These two forms differ in a couple of key areas explained below.


Methylcobalamin is the best absorbed form of supplemental B12 in the body because it is bioactive. In other words, its readily available to positively interact with our cells.

This form has a chemical structure that has a methyl group, which consists of a hydrogen and oxygen molecule. This methyl group makes it the most active form of Vitamin B12 in the body.

Methylcobalamin is also the most common form of B12 found in animal foods, which is why meat eaters dont need to supplement.


The only synthetic form of Vitamin B12, cyanocobalamin differs greatly than other forms because its chemical structure contains cyanide.

This cyanide group is the same as the poisonous cyanide youve heard of before, but irrelevant to the body at the levels found in Vitamin B12. It is also the only form of Vitamin B12 that gets created in a lab setting.

The synthetic nature of this form requires more steps in the breakdown of Vitamin B12 and could potentially cause absorption issues.

Cyanocobalamin is used in supplements for years due to its proposed effectiveness. Although more recently, criticisms in the scientific community have started to surface about its:

Taking Sublingual Vitamin B12

Solgar, Sublingual Methylcobalamin (Vitamin B12), 5,000 ...

In addition to the traditional route of absorption through the intestinal mucosa, vitamin B12 can also be absorbed through the oral mucosa. In theory, this can be advantageous if absorption via digestion is impaired, as it allows the B12 to bypass the intestine.

Just how much vitamin B12 can be absorbed through the oral mucosa and how much is simply swallowed down into the intestine has not yet been researched. However, it is certain that sublingual absorption is at least as effective as a normal oral intake .

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How Much Vitamin B12 Do You Really Need

These recommendations come from the Food and Nutrition Board at the Institute of Medicine of the National Academies. They will meet the needs of 98% of healthy people.

However, those with unique medical conditions should speak with their doctor for specific dosing protocols.

Recommended Daily Intake for Healthy Adults:

  • 2.4 mcg per day

Additionally, pregnant women need slightly more at 2.6 mcg per day and lactating women need 2.8 mcg per day.

Supplementation Guidelines

Most Vitamin B12 supplements start at least 250 mcg and go as high as 5000 mcg per dose.

Choose one of the two dosing guidelines for Vitamin B12:

  • 250 mcg per day OR
  • 2500 mcg per week

Typically, people choose the once per week option because most supplements come in higher doses. With that, you will find the best value for your dollar and can avoid supplementing with pills daily.

Its also best to take Vitamin B12 supplements during the day since they stimulate the nervous system and can cause a caffeine-like effect in the brain.

Some people report trouble sleeping if taken too late in the day. As a rule of thumb, take the supplement before 1 p.m.

How Long Should I Take Vitamin B12 Supplements

The usual dose for pernicious anemia-associated vitamin B12 deficiency is 100 mcg given as an injection into the muscle or under the skin once daily for 6-7 days. Then the dose may be given every other day for 7 doses followed by every 3-4 days for around 3 weeks. Then, 100 mcg should be injected every month for life.

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Ultra Absorption Vitamin B12 With Folic Acid

SimplyPure Ultra Absorption Mega Vitamin B -12 g with Folic Acid Sublingual Lozenges at the highest dosage of 5000 mcg as Methylcobalamin. These small strawberry flavor vegetarian tablets dissolves in your mouth with no after taste and is active immediately upon absorption.

Vitamin B12 with Methylcobalamin Lozenges is a water soluble Vitamin necessary for the maintenance of a healthy nervous system and for the metabolic utilization of fats and proteins. Adequate intake of Vitamin B-12, along with Folic Acid, encourages healthy serum homocysteine levels, thereby supporting cardiovascular health.

  • Supports increased Energy Levels and combat fatigue*
  • Helps regulate formation of red blood cells and metabolism*
  • Promote Healthy Eye Sight*
  • Support to control homocysteine levels*

Mega Vitamin B12 B6 is also essential for the synthesis during cell division and therefore is especially important for rapidly multiplying cells such as blood cells. In addition, adequate intake of Vitamin B12, along with Folic Acid and Vitamin B6, encourages healthy serum homocysteine levels, thereby supporting cardiovascular health. Because Vitamin B12 is found predominantly in animal products, strict vegetarians are at risk of developing Vitamin B12 deficiency and may benefit from supplementation.

Is Vitamin B12 Dosage 5000 Mcg Safe

Review of Liposomal Vitamin B12 Sublingual 5000 mcg Liquid Drops, Energecko Vegan B12 Liquid

This post may contain affiliate links. Please read my disclosure for more information.

Definition | Forms of B12 | How B12 is Processed | Deficiencies | Benefits | Food Sources | How Much Do You Need | Is Vitamin B12 5000mcg Safe? | Supplements | Wrap Up

Vitamin B12 supplementation has exploded recently due to the popularity of plant-based diets. Since this vitamin is hard to get strictly through plant foods, medical professionals everywhere recommend supplementing Vitamin B12 for those who follow a vegan, vegetarian, or plant-based diet.

With single serving doses on supplement bottles ranging greatly, its confusing to know how much to take on a daily or weekly basis. Additionally, ingesting high quantities of a supplement could have negative health consequences.

Is Vitamin B12 dosage 5000 mcg safe?

This post will answer that question and explore the risks, benefits, origins, dosing guidelines, and the best supplement recommendations for Vitamin B12.

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Disadvantages Of Sublingual Vitamin B12 Supplements

Many sublingual products contain additives, such as flavourings and colourings, which are obviously not always desirable. An overview of the current additives used in various B12 supplement forms can be found in the following articles:

As a general rule, strips and lozenges contain the most additives, whilst drops and sprays tend to have less. Readers who want to use the more comfortable methods of absorption, but would prefer to avoid additives, are therefore best advised to use drops or sprays.

How Does Your Body Process Vitamin B12

The most prominent source of Vitamin B12 is found in animals products.

Animals get the B12 in two ways: eating grass that has B12 in the soil or through supplementation in their feed. The latter being the most common practice in our world today.

Food Absorption

Since humans still eat animals, they get Vitamin B12 through their food. For example, when a person eats meat, the Vitamin B12 in that animals tissue enters the stomach.

This B12 is protein-bound, meaning it attaches itself to a protein molecule for transport. Before it enters the small intestine, it has to detach in the stomach.

Once the B12 detaches from the protein in the stomach, its picked up by a different protein molecule called intrinsic factor .

IF then enters the small intestine bound to Vitamin B12 and gets separated once again into a group called corrinoids .

These separated corrinoids attach one more time to a different form of IF and heads to its destination in the small intestine.

Once there, the receptors in the small intestine give the corrinoids first priority to absorb. This ensures the body gets this crucial vitamin over other nutrients that have passed through at the same time.

Supplement Absorption

The supplemental form of B12 gets absorbed much easier through supplements than food. Thats because its not bound to protein like in animal tissue.

This makes the supplemental form of Vitamin B12 the most reliable form we have available.

  • Paralysis
  • Death

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Active Ingredients In Sublingual Vitamin B12 Supplements

There is a range of B12 active ingredients used in sublingual supplements to choose from. Here is a short overview:

B12 Form

No, artificial form

No, 4 conversion steps

Produces a small amount of cyanide, therefore not suitable for smokers or for detoxification. General effectiveness is proven, but worst absorption rate and long-term effectivity

Can be difficult to find supplements containing this form

How Should I Use Methylcobalamin

Methylcobalamin (Vitamin B12) 5000 mcg, Sublingual

Use exactly as directed on the label, or as prescribed by your doctor.

Methylcobalamin oral is taken by mouth.

Methylcobalamin injection is injected into a muscle, usually 1 to 3 times per week. A healthcare provider can teach you how to properly use the medication by yourself.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don’t understand all instructions.

Do not swallow a lozenge, disintegrating tablet, or sublingual tablet whole. Allow it to dissolve in your mouth without chewing. The sublingual tablet should be placed under your tongue.

Your dose needs may change if you become pregnant, if you breastfeed, or if you eat a vegetarian diet. Tell your doctor about any changes in your diet or medical condition.

For more information you may also consult the Office of Dietary Supplements of the National Institutes of Health, or the U.S. Department of Agriculture Dietary Reference Intakes listings for more information.

Store at room temperature away from moisture and heat.

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Top Choices Of Vitamin B12 Methylcobalamin Brands

All of the following choices are suitable for vegans and are the purest formulas available with no harmful ingredients, like animal by-products, GMOs, preservatives, colors/dyes, artificial flavors, or common allergens. They are listed in alphabetical order, and not in any order of preference. Note that this list is not exhaustive of all of the possible good choices out there it is focused on brands that I am familiar with that are common in Canada and the United States. Formulas may change at any time, so be sure to read the ingredients of the actual product package you are interested in before buying. Any product chosen should be based on what you feel would be the best choice for you, taking into consideration the supplement form, dose, flavor, price, and availability in your area.

Product: B12 Methylcobalamin 1,000 mcg Lemon Tablets sublingualFeatures: With vitamin B6 and folateOther Ingredients: Xylitol, Mannitol, Lemon Flavor, Crospovidone, Citric Acid, Sodium Citrate, Vegetable Magnesium Stearate, Silica.

Other Ingredients: Xylitol, Cellulose, Stearic Acid , Natural Cherry Flavor, Citric Acid, Magnesium Stearate .


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