Assessment Of Vitamin C And Diet
To assess dietary intake including vitamin C intake, we used a semiquantitative food-frequency questionnaire that inquired about the average use of > 130 foods and beverages during the previous year., , In addition, respondents provided information on the use of supplemental vitamins, taken either alone or in multivitamin form. The baseline dietary questionnaire was completed in 1986 and was updated every four years. Nutrient intake was computed from the reported frequency of consumption of each specified unit of food or beverage and from published data on the nutrient content of the specified portions. For supplemental vitamin C, respondents chose from the following categories: 0, 1 to 399, 400 to 700, 750 to 1250, and 1300 mg or more daily. The amount of vitamin C in multivitamin preparations was determined by the brand, type, and frequency of reported use. Food and nutrient intakes assessed by this dietary questionnaire have been validated previously against two 1-week diet records in this cohort., Specifically, the Pearson correlation coefficient for energy adjusted total vitamin C intake between the dietary records and the questionnaire was 0.86. After adjustment for the week-to-week variation in vitamin C intake the correlation coefficient was 0.92. After excluding supplemental vitamin use the correlation coefficient for vitamin C was 0.77.
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Dietary Approaches To Control Hyperuricemia And Reduce Gout Risk
Lifestyle can have a significant influence on the development of hyperuricemia and gout. Accumulated data from several large epidemiological studies suggest several possible modifications for significant reductions in gout risk56:
Exercise daily and reduce weight. Increased adiposity is associated with increased uric acid levels and gout risk.
Limit red meat intake. Beef, pork, and lamb are high-purine foods that can significantly increase gout risk.
Adjust fish intake to individual needs. Carefully balance the benefits of omega-3 fatty acids with the increased gout risk or consider taking an omega-3 supplement. High quality fish oil supplements are highly purified and the purine content in these oils is either undetectable, or present in trace amounts that pose no risk of raising gout levels.
Drink skim milk or consume other low-fat dairy products. Dairy consumption is inversely associated with gout risk.
Consume vegetable protein, nuts, and legumes. Nuts and legumes are good sources of non-uricemic protein legumes and vegetables are not associated with gout risk.
Reduce alcohol intake. Moderate alcohol consumption has cardiovascular benefits, but beer and spirits significantly increase gout risk. Red wine, on the other hand, appears not to increase gout risk.
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How To Reduce Uric Acid With Vitamins
Excessive uric acid in a person’s body can lead to uric acid crystals forming in the joints and in tissue surrounding the joints 3. This condition is known as gout, a type of arthritis involving sudden attacks of severe joint pain and inflammation. Gout usually develops after years of high uric acid production associated with diet, and some people are more susceptible than others to this condition 3. If you are overweight, losing weight can help reduce uric acid 3. Avoiding foods high in purines, such as many types of meat and fish, can also decrease uric acid 3. Certain vitamins also can affect uric acid levels 3.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Take vitamin C supplements. Research has shown that vitamin C is associated with reduced uric acid levels, such as a study published in the September 2008 issue of the Journal of Rheumatology 13. This study found that men taking up to 500 mg of vitamin C daily had lower serum uric acid concentrations than men who did not 3. Larger dosages did not result in more significant changes.
Avoid taking large amounts of vitamin B3 supplements, since doses of 300 mg and higher have been linked to increased uric acid levels 3. The recommended daily allowance, commonly included in multivitamins, is 100 mg.
How Tart Cherry Extract Provides Relief
For those suffering from gout, you may find relief with the power of tart cherries . In fact, studies suggest that about 25% of people with gout use these and want to avoid problems with pharmaceuticals. Tart cherries have been noted for their aid in alleviating symptoms of gout thanks to their rich antioxidant content and anti-inflammatory powers.
These small fruits help to alleviate inflammation, a key element of a gout attack.
Scientists believe that part of the reason cherries might work is that they increase the excretion of urate and also limit the production of uric acid in the liver. The abundant urate crystals in those with gout stimulate the production of pro-inflammatory cytokines.
Cherry counteracts this problem and also protects the body and joints by providing good antioxidant coverage. This is an excellent non pharmacological option for the treatment of many of the problems associated with gout.
Tart cherries have many phytochemicals that help, but cyanidin is the most prevalent compound. These nutrient-rich cherries help to reduce inflammation and oxidative stress in the body and may even help to offset the effect of gout on the bones and joints.
Reach for a bowl of fresh Montmorency cherries, a glass of sugar-free tart cherry juice, or a tart cherry supplement to stay on top of your symptoms. Tart cherries are not just for good gout but also insomnia, muscle pain, and over-exertion, and they offer an excellent way to help the body recover.
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Tart Cherry Extract: A Natural Option For Gout Relief
You are suffering from pain and inflammation in your feet, most notably in your big toe. This pain can be moderate to severe and come on suddenly, wracking you with hot, stinging sensations.
You are experiencing the symptoms of gout. This is called podagra. In Greek, podagra means foot trap. Now you know what this feels like it feels as though your big toe has been caught in a steel trap.
How can you find relief? Lets look at what gout is and how you can fight its symptoms naturally with tart cherry extract.
How To Prevent Gout Attacks
To prevent gout attacks, limit your consumption of sugars.
Drink plenty of fluids, with water being your best choice.
Do your best to control emotional and physical stress, as this can cause your flare-ups to be even more severe, and consult your personal physician to help control the pain and keep your condition from worsening.
Treatments for gout have advanced over the years, including the development of allopurinol, a drug to prevent attacks. Speak with your orthopedic surgeon or personal physician about possible pharmaceuticals for gout. Many people with gout suffer from multiple conditions and medication interactions and side-effects should be considered.
Thankfully, there is a natural remedy for the symptoms of gout available, as well.
The Role Of Hyperuricemia In Other Conditions
Although hyperuricemia is most often associated with gout, elevated blood levels of uric acid have also been associated with other diseases. Hyperuricemia and gout are both risk factors for kidney or bladder stones . Both conditions increase the risk of forming not only uric acid stones, but also the more common calcium oxalate stones. The presence of calcium oxalate stones is 10â30 times higher in gout patients than those without gout.25 Deposits of monosodium urate crystals in kidney tissues can result in kidney damage , either acutely by formation of crystals within the tubules of the kidney, or through a chronic inflammatory response to urate deposits in other tissues of the kidney.26 Prior to the development of uric acid lowering treatments, kidney disease occurred in up to 40% of gout patients renal failure was the usual cause of death in 18â25% of these patients.7
Hyperuricemia is an integral part of metabolic syndrome,20 and epidemiological studies have demonstrated that elevated uric acid levels substantially increase metabolic syndrome risk .33,34 Data from the Multiple Risk Factor Intervention Trial showed hyperuricemia was associated with increased risk of type 2 diabetes, and that male patients with gout had a 41% increased risk for the disease.35
Supplements That Lower Uric Acid
Uric acid is a product of purine breakdown. Purines are aromatic organic compounds found in certain foods and beverages. Medline Medical Encyclopedia states that a significant amount of uric acid in your body dissolves in your blood and is excreted in your urine, but if your body produces too much uric acid or is unable to rid itself of uric acid, you can develop a condition known as hyperuricemia 1. Ask your doctor if supplements can help resolve your hyperuricemia.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
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Association Of Gout With Vitamin D: A Population
Jinan Al-Naqeeb1, Mohammed Saeed 2, Beata Dye 3 and Mark Jeranko 4, 1Ascension St John hospital, Grosse Pointe Park, MI, 2Capital Health hopsital, Trenton, NJ, 3Ascension St John Hospital, Detroit, MI, 4Detroit Medical Center/ Wayne State University, Detroit, MI
Session Type: Poster Session
Session Time: 9:00AM-11:00AM
Background/Purpose: Prior research showed conflicting results about the association of vitamin D with gout. We aimed in this study to quantify vitamin D levels in patients with and without gout using nationally representative data.
Methods: The National Health and Nutrition Examination Survey is a nationally representative sample of the non-institutionalized population in the United States. We analyzed data from 2011 to 2014 for adults . Gout was defined as a yes to: Has a doctor or other health professional ever told you that you had gout?. Gender, age, vitamin D level, and vitamin D supplement use in the past 30 days were identified. Vitamin D deficiency was defined as < 50 nmol/L and high vitamin D level was defined as > 125 nmol/L. Survey-specific statistical methods were used to account for sample design. Mean vitamin D levels and low/high vitamin D prevalence were calculated for people with and without gout. The Chi-square test was used to test the difference between categorical variables with alpha=0.05.
Disclosure:J. Al-NaqeebM. SaeedB. DyeM. Jeranko
To cite this abstract in AMA style:
But Is Benefit Possible Through Dietary Sources
While dietary mistakes can trigger gout attacks, the avoidance of trigger foods will help prevent them. Similarly, the amount of vitamin C obtainable through the diet should, over time, help reduce blood levels of uric acid and therefore make an attack less likely. Can we get to 500mg through dietary sources? Easy.
- Kale is the latest wonder veg. 100g of it will give 120mg vitamin C.
- 110g Broccoli will deliver 100mg vitamin C .
- Guavas come in different sizes, but just 100g will supply a huge 228mg of vitamin C.
- Standard servings of various berries, citrus fruits such as oranges, green leafy veg, a kiwi and peas will all provide around 60-100mg of vitamin C too, so its incredibly easy to eat enough to lower uric acid.
Cant imagine eating fruit every day? Try buying a bag of frozen berries, or some kale and pop a handful into a blender for a breakfast smoothie. Here are 4 delicious examples:
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Eat Foods With Less Purines
Purines are chemicals that are naturally produced by your body and are also found in certain foods. Animal purines from meat and seafood can especially affect your uric acid level.
“Most people eat more than they think,” says Dr. Monya De, an internist in Los Angeles.
The following foods contain high amounts of purine, so those seeking to lower their uric acid level should avoid or limit eating them:
- Organ meat like liver or kidneys
- Shellfish and oily fish such as anchovies and tuna
- Some vegetables, including asparagus, mushrooms, and spinach
On the other hand, the following foods contain low amounts of purine, so eating them won’t increase your uric acid level:
- Nuts and peanut butter
- Low-fat or nonfat dairy products including cheese, milk, and yogurt
- Cherries and other fruits
Following a healthy diet can also help lower your uric acid levels. For example, a 2016 study published in the American College of Rheumatology journal Arthritis & Rheumatology found that following the DASH diet for 30 days helped people with prehypertension and hypertension lower their uric acid level by as much as 1.3 mg/dL.
What Can I Do To Avoid Gout Attacks
Your doctor can prescribe medicines to prevent future gout attacks. These medicines wash the uric acid from your joints, reduce the swelling or keep uric acid from forming.
You should lose weight if you need to. If you have high blood pressure or high cholesterol, get treatment and follow a low-salt, low-fat diet.
Stay away from alcohol and foods that are high in purines.
Drinking lots of water can help flush uric acid from your body.
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Foods That Reduce Uric Acid
Keep in mind that uric acid crystals form after the breakdown of purines. In fact, purines are known to increase the level of uric acid in the blood. Since some purines are taken in through the diet, a low uric acid diet is also a low-purine diet. With that being said, here are the best foods that will help lower uric acid levels in your blood:
Cherries are among the top foods that lower uric acid levels. They help prevent uric acid crystallization in the joints and they contain powerful compounds called bioflavonoids, proanthocyanidins, and anthocyanins. In a 2012 study published in the journal Arthritis Rheumatism, researchers discovered that cherry consumption reduced gout attacks by 35% in 633 people with gout.
2. Apple cider vinegar:
Apple cider vinegar should also be included in a low-uric acid diet. The malic acid in apple cider vinegar is thought to help break down and remove uric acid from the body. It also contains antioxidant and anti-inflammatory properties. It is best to add one to three teaspoons of raw, organic, unpasteurized apple cider vinegar to eight ounces of water. Drink the apple cider mixture two to three times daily to help control uric acid. In general, apples can also help control uric acid levels.
3. Lemon juice:
4. Olive oil and olives:
5. Organic eggs:
Eggs are considered a low purine food and should be included among the foods that lower uric acid.
7. Brazil nuts:
8. Pinto beans:
Herbs Which Can Help In Dissolving Uric Acid:
1. Lemon herbs
Vitamin C rich lemon herbs can reduce inflammation in the body by increasing formation of calcium carbonate in the body. Lemon juice can be made using herbs. Lemon juice contains citric acid, an organic substance which can help in dissolving uric acid crystals. It also decreases concentration of uric acid in the body. Vitamin C strengthens the connective tissue and reduces pain in joints. One glass of fresh lemon juice every day can help in dissolving uric acid.
2. Devil’s claw
Devil’s claw is a naturally occurring substance which reduces inflammation in affected areas of the body. It has been proven effective in treating symptoms of various types of arthritis, including gout. Uric acid may be effectively reduced in the blood and be dissolved using devil’s claw. Devil’s claw is in fact even recommended to those with osteoarthritis. Take this herb according to the instructions of a herbalist.
3. Burdock root
Burdock root is a frequently recommended herb for treating acute gout attacks. Burdock root has properties which enable the excess uric acid to pass through the urine. This herb is also very useful to cleanse toxins from the blood and reduce inflammation. Not only is burdock root helpful in dissolving uric acid, it is also helpful in treating gout.
4. Sour black cherries
5. Alfalfa sprouts
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Cherries May Lower Uric Acid
Because small experimental studies have shown that cherries lower uric acid levels, researchers sought to determine whether eating cherries reduces gout attacks. Investigators evaluated cherry consumption in more than 600 people with gout and published their findings in the December 2012 issue of the journal Arthritis and Rheumatism. They found that consuming cherries daily resulted in a 35 percent lower risk of recurrent gout attacks. Combining cherry intake with the use of the gout medication allopurinol reduced gout attacks by 75 percent, according to the study.
Ascertainment Of Incident Cases Of Gout
We ascertained incident cases of gout by the American College of Rheumatology survey gout criteria, as previously described. Briefly, on each biennial questionnaire, participants indicated whether they had received a physician diagnosis of gout. We mailed to those subjects with self-reported incident gout 1986 onwards a supplementary questionnaire to confirm the report and to ascertain the American College of Rheumatology survey gout criteria., The primary end point in this study was an incident case of gout that met 6 or more of the 11 gout criteria., To confirm the validity of the survey gout criteria in our cohort, we reviewed the relevant medical records from a sample of 50 of the men who had reported having gout. The concordance rate of confirming the report of gout between the gout survey criteria and the medical record review was 94% .
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